By around age 10, Duchenne patients typically exhibit which of the following symptom combinations?

• A. Falling; Fatigue; Ambulation only household distances
• B. Increased energy; Improved gait; Faster walking
• C. Late onset of symptoms; No fatigue; Normal ambulation
• D. There are no typical age-related symptoms

Answer: (A)

Duchenne muscular dystrophy causes progressive proximal muscle weakness that starts in early childhood and worsens over time. By around age 10, many boys have developed enough leg and hip weakness to cause frequent falls, report tiredness with walking, and can ambulate only short distances within the home. This pattern of functional decline—falls, fatigue with activity, and limited ambulation to household distances—reflects the typical progression of the disease at this age. The other options describe energy increases, late onset with normal walking, or no age-related symptoms, which do not fit the known course of Duchenne.