In Duchenne muscular dystrophy, which muscle group is typically affected first?

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Multiple Choice

In Duchenne muscular dystrophy, which muscle group is typically affected first?

Explanation:
Duchenne muscular dystrophy causes progressive weakness that starts in proximal muscles, the ones closest to the trunk and essential for movement. In this condition, the hip and thigh muscles—parts of the lower extremities—are the first to show weakness because they’re heavily engaged in standing, climbing, and walking. Patients often develop a Gowers maneuver when rising from the floor, reflecting this proximal leg weakness. As the disease progresses, upper limbs, neck, and facial muscles become more involved, but the earliest affected group is the proximal muscles of the lower extremities.

Duchenne muscular dystrophy causes progressive weakness that starts in proximal muscles, the ones closest to the trunk and essential for movement. In this condition, the hip and thigh muscles—parts of the lower extremities—are the first to show weakness because they’re heavily engaged in standing, climbing, and walking. Patients often develop a Gowers maneuver when rising from the floor, reflecting this proximal leg weakness. As the disease progresses, upper limbs, neck, and facial muscles become more involved, but the earliest affected group is the proximal muscles of the lower extremities.

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